Lenovo Thinksystem Sr645 Server
Overview
Product sourcing insights & recommendations
I have synthesized a comprehensive product and market insight report for the Lenovo ThinkSystem SR645 and its latest successor, the SR645 V3.
Key Insights
* Technological Evolution: The transition to the SR645 V3 introduces a massive jump in core density—from 128 cores to 320 cores per system—and upgrades to DDR5 and PCIe 5.0, providing double the I/O bandwidth for data-intensive workloads.
* Market Leadership: The SR645 V3 currently holds 4 world records for energy efficiency, making it one of the most performance-per-watt efficient 2-socket 1U servers in the 2026 market.
* Cost Advantage: Industry data suggests Lenovo's SR645 platform offers a significant value proposition, with chassis costs approximately 40% lower than comparable models from major competitors like Dell, despite delivering similar performance benchmarks.
* Workload Optimization: While the original SR645 remains a high-value option for standard virtualization, the V3 model is specifically optimized for AI inference, High-Performance Computing (HPC), and Cloud Service Provider (CSP) density.
The attached report provides a detailed technical comparison, competitive analysis, and strategic sourcing recommendations for your reference.
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Lenovo ThinkSystem SR645 Server Product Guide (withdrawn product) ...
lenovopress.lenovo.com
The Lenovo ThinkSystem SR645 is a 2-socket 1U server that features the AMD EPYC 7002 "Rome" and AMD EPYC 7003 "Milan" families of processors. With up to 64 cores per processor and support for the new PCIe 4.0 standard for I/O, the SR645 offers the ultimate in two-socket server performance in a space-saving 1U form factor. The following figure shows the locations of key components inside the server. Figure 4. Internal view of the Lenovo ThinkSystem SR645 · The following figure shows the architectural block diagram of the SR645, showing the major components and their connections. Figure 5. SR645 system architectural block diagram · The following table lists the standard specifications. The onboard SATA controller has the following features: ... For specifications about the RAID adapters and HBAs supported by the SR645, see the ThinkSystem RAID Adapter and HBA Reference, available from: https://lenovopress.com/lp1288-lenovo-thinksystem-raid-adapter-and-hba-reference#sr645-support=SR645 AI and HPC base models are intended for Artificial Intelligence (AI) and High Performance Computing (HPC) configurations and solutions are enabled using the AI & HPC Hardware - ThinkSystem Hardware mode in DCSC. These configurations, along with Lenovo EveryScale Solutions, can also be built using System x and Cluster Solutions Configurator (x-config). Tip: Some HPC and AI models are not listed in DCSC and can only be configured in x-config. Preconfigured server models may also be available for the SR645, however these are region-specific; that is, each region may define their own server models, and not all server models are available in every region.
Lenovo ThinkSystem SR645 V3 Server Product Guide > Lenovo Press
lenovopress.lenovo.com
The Lenovo ThinkSystem SR645 V3 is a 2-socket 1U server that features the 5th Gen AMD EPYC 9005 "Turin" family of processors. With up to 160 cores per processor and support for the new PCIe 5.0 standard for I/O, the SR645 V3 offers the ultimate in two-socket server performance in a 1U form factor. The following figure shows the locations of key components inside the server. Figure 5. Internal view of the Lenovo ThinkSystem SR645 V3 · The following figure shows the architectural block diagram of the SR645 V3, showing the major components and their connections. Figure 6. SR645 V3 system architectural block diagram · The following table lists the standard specifications. Memory operates at the speed of the memory bus of the processor (see the Processor features section for specifics), or the maximum speed that the memory DIMMs support (see the above tables), whichever is lower · The use of the 128GB 3D RDIMM feature BYEE has the following requirements for thermal reasons: ... Additional ambient temperature requirements - see https://pubs.lenovo.com/sr645-v3/thermal_rules for information · When adding the ThinkSystem 256GB TruDDR5 6400MHz (4Rx4) 3DS RDIMM-A (4X77B07422) as a field upgrade, follow the instructions in Support tip TT3220 The SR645 V3 has a total of 4 current performance benchmark world records. Results referenced are current as of September 1, 2026. See the complete list of current world records in the Lenovo Press article Performance Benchmark World Record Summary for Lenovo ThinkSystem Servers. The Lenovo Server Performance Team also publishes reports on key performance world records at the time the world record is announced.
Lenovo ThinkSystem SR645 Server
www.itcreations.com
Flexible storage configurations on the Lenovo ThinkSystem SR645 server make it easier to handle critical hybrid data center workloads such as virtualization and database. This dual processor system also features AMD EPYC processors from the 7002 or 7003 series, providing extreme levels of core and memory density, all in a 1U chassis. The Lenovo ThinkSystem SR645 is a 1U, 2-socket server powered by the latest AMD EPYC 7003 series processors or the previous 7002 series. Each CPU contributes 8 to 64 cores, coupled with fast memory speeds and 128 PCIe Gen 4.0 lanes. This allows the SR645 to deploy up to 3x single-width NVIDIA GPUs and plus NVMe drives. The system’s reliability is backed by Lenovo’s XClarity management capabilities, which adds an extra layer of security to the data center. The ThinkSystem SR645 can house two second- or third-generation AMD EPYC processors, codenamed “Rome” and “Milan.” Each CPU contributes 8 to 64 physical cores and 16 to 128 virtual threads, for a total of 128 physical cores on the motherboard with top-tier 64 core CPUs installed. Up to 3x PCIe 4.0 slots, all with rear access, are available on the ThinkSystem SR645 server. Similarly, a maximum of 3x single-width 75W GPUs can be installed including NVIDIA’s A2, T4, and Quadro P620 cards, but the GPUs must be identical as mixed GPU implementations are not supported. Moreover, there is an internal bay for a cabled RAID adapter or HBA, plus a slot dedicated to an OCP 3.0 SFF mezzanine slot for additional network connection options. Administrators can use Lenovo’s XClarity management software to help make the deployment, management, and servicing of the system simple and highly secure.
Features | ThinkSystem SR645 | Lenovo Docs
pubs.lenovo.com
The server has an Open Compute Project (OCP) 3.0 slot for an OCP 3.0 Ethernet adapter, which provides one to four network connectors for network support. ... This integrated security chip performs cryptographic functions and stores private and public secure keys. It provides the hardware support for the Trusted Computing Group (TCG) specification. The server supports a maximum of eight hot-swap power supplies, which provide redundancy for a typical configuration. The redundant cooling by the fans in the server enables continued operation if one of the fans fails. ... The ThinkSystem RAID adapter provides hardware redundant array of independent disks (RAID) support to create configurations. Lenovo ThinkSystem servers are capable of booting UEFI-compliant operating systems, BIOS-based operating systems, and BIOS-based adapters as well as UEFI-compliant adapters. If a Features on Demand feature is integrated in the server or in an optional device that is installed in the server, you can purchase an activation key to activate the feature.
ThinkSystem SR645 Datasheet (withdrawn product) > Lenovo Press
lenovopress.lenovo.com
The Lenovo ThinkSystem SR645 is powered by two AMD EPYC™ 7003 Series CPUs in a compact 1U rack server form factor maximizing CPU core and memory density. These features deliver the next era of solution performance for enterprise data center operations such as database, analytics and virtualization workloads. Lenovo’s lauded system reliability, XClarity management capabilities, and security infrastructure layer add to the exceptional value that the ThinkSystem SR645 brings to the data center. The modern data center demands ever-expanding capability, requiring server technology to deliver more performance that tests the limits of physics. With the enterprise-class AMD EPYC™ 7003 Series processor, the new standard for the modern data center CPU, the ThinkSystem SR645 features an unprecedented 128 cores and 128 Gen4 PCIe lanes in a server to maximize server utilization and decrease network bottlenecks in HPC workloads. Trust Lenovo ThinkShield to protect and defend your data center infrastructure from attacks, with a comprehensive end to end approach to security that begins with development and continues through supply chain and the full life cycle of the server. AMD EPYC processors also offer unique security features, embedded with secure boot and full memory encryption capabilities to address growing security-threats. Finally, Lenovo’s portfolio of services support the full lifecycle of your Lenovo IT assets - from planning, deployment and support to asset recovery. For more details please see the ThinkSystem SR645 product guide.
Technical specifications | ThinkSystem SR645 | Lenovo Docs
pubs.lenovo.com
